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By my4kids On 2009.02.15 20:27
Wondering if anyone from this great forum can help offer some input/advice. My husband takes Seroquel...100mg in late afternoon for agitation and 100mg at bed which has made sleep much less of an issue. I need to refill but have 2 concerns. One is weight gain...he's gained 60 - 70 pounds over the last year. The other is cost! My question is if anyone knows of a generic med which is much less expensive and might help as well as the seroquel w/out the side effect of weight gain. I plan on asking the Dr tomorrow but I like to have some input before I call in. When I mentioned weight gain to his neuro he seemed to think it was boredom/stress eating, but while never the healthiest eater, pre seroquel and pre-pd he had some weight up and downs, but it was more of a 15 - 25 fluctuation, and was from what he ate, not the frequency and quantity that he seems to eat know. Among other meds, he takes requip, which had caused internet/ebay excessive buying, but since we reduced that to 1.5 mg / day (and added 50mg Stalevo 3x daily), that problem pretty much disappeared. I thought perhaps the eating issue might also subside, but the reduction in requip didn't seem to make a difference. Hence, my conclusion that it's the seroquel. He's put on another ten since just before Christmas, and that was when we added another 50mg in the afternoon for agitation. We absolutely have to have something to control that, because prior to the seroquel (or if he doesn't take it on time), come 4pm, too much noise, commotion or disagreement w/ the myself or the kids has him yelling, ranting, etc. The tremendous weight gain exacerbates his back and arthritis problems and I'm sure will add to more health issues, but more than that, I know it's makes him feel much worse about himself and is really limiting his activity. Any advice would be appreciated. Thanks so much...

By bandido1 On 2009.02.16 13:14
I am probably too late but my neuro RX'd Clonozepam for REM sleep disorder I was experiencing from either Requip or Stalevo. Bob C Ask your doctor.

By caregivermary On 2009.02.16 14:12
My husb takes serequel(200mg) at night and hasn't gained a pound. In fact, he keeps losing weight. I guess, as it has been mentioned on this forum before everyone is affected in differents ways.

I don't think there is a generic for this drug and as I understand from the reading I do that this is the best drug for the issues your husb is experiencing. I would, however, follow the advice and ask your Neuro.

By rajenriver On 2009.02.17 13:41
One of the side effects of some of the PD medications is obsessive compulsiveness. I am sure that you have seen the comments on gambling, sex obsession, etc. My FIL gained weight because he would drink 1-2 qts of chocolate milk and 1/2 gal of icecream in a day. Not to mention all the other goodies he enjoyed in between. Now that he is in a nursing home and he can't get all those treats at one time, his weight is much better.
-Jenny

By annwood On 2009.02.17 19:39
My guess would be that his compulsive behavior has changed from ebay to eating. Weight gain is not a side effect of Serequel.


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